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Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy_repos |
| Phenotype | phenotype_absentNotch_versus_normalThy.cls#absentNotch_versus_normalThy_repos |
| Upregulated in class | normalThy |
| GeneSet | NCI_SIGNALING EVENTS MEDIATED BY STEM CELL FACTOR RECEPTOR (C-KIT) |
| Enrichment Score (ES) | -0.7016323 |
| Normalized Enrichment Score (NES) | -1.5218163 |
| Nominal p-value | 0.013856813 |
| FDR q-value | 0.22206594 |
| FWER p-Value | 0.978 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | GRB2 | 6650398 | 1188 | 0.612 | -0.0190 | No | ||
| 2 | STAT5A | 2680458 | 1375 | 0.523 | 0.0094 | No | ||
| 3 | RAF1 | 1770600 | 2375 | 0.227 | -0.0277 | No | ||
| 4 | MAP2K2 | 4590601 | 2672 | 0.174 | -0.0309 | No | ||
| 5 | CREBBP | 5690035 7040050 | 3086 | 0.119 | -0.0444 | No | ||
| 6 | MAPK8 | 2640195 | 3135 | 0.114 | -0.0386 | No | ||
| 7 | BAD | 2120148 | 3409 | 0.089 | -0.0467 | No | ||
| 8 | PTPRO | 1940576 6370332 | 3415 | 0.089 | -0.0405 | No | ||
| 9 | KIT | 7040095 | 3619 | 0.075 | -0.0459 | No | ||
| 10 | RPS6KB1 | 1450427 5080110 6200563 | 3919 | 0.057 | -0.0578 | No | ||
| 11 | JAK2 | 3780528 6100692 6550577 | 4243 | 0.044 | -0.0719 | No | ||
| 12 | HRAS | 1980551 | 4798 | 0.029 | -0.0996 | No | ||
| 13 | SNAI2 | 2100519 | 5562 | 0.018 | -0.1394 | No | ||
| 14 | EPOR | 5290435 | 6101 | 0.014 | -0.1673 | No | ||
| 15 | GRAP2 | 7100441 1410647 | 6709 | 0.010 | -0.1992 | No | ||
| 16 | EPO | 940180 | 6911 | 0.009 | -0.2094 | No | ||
| 17 | PTPN11 | 2230100 2470180 6100528 | 7257 | 0.008 | -0.2274 | No | ||
| 18 | LYN | 6040600 | 7424 | 0.007 | -0.2358 | No | ||
| 19 | PIK3R1 | 4730671 | 7437 | 0.007 | -0.2359 | No | ||
| 20 | AKT1 | 5290746 | 7797 | 0.006 | -0.2548 | No | ||
| 21 | MAP2K1 | 840739 | 8060 | 0.005 | -0.2685 | No | ||
| 22 | DOK1 | 1050279 2680112 5220273 | 9547 | 0.001 | -0.3485 | No | ||
| 23 | GRB10 | 6980082 | 10821 | -0.003 | -0.4168 | No | ||
| 24 | SOS1 | 7050338 | 11108 | -0.004 | -0.4319 | No | ||
| 25 | SPRED1 | 6940706 | 11552 | -0.005 | -0.4554 | No | ||
| 26 | MITF | 380056 | 11682 | -0.006 | -0.4619 | No | ||
| 27 | PIK3CA | 6220129 | 12684 | -0.010 | -0.5151 | No | ||
| 28 | KITLG | 2120047 6220300 | 13878 | -0.021 | -0.5778 | No | ||
| 29 | SHC1 | 2900731 3170504 6520537 | 13907 | -0.021 | -0.5777 | No | ||
| 30 | SH2B3 | 4810451 4850128 | 14516 | -0.032 | -0.6080 | No | ||
| 31 | FOXO3 | 2510484 4480451 | 14837 | -0.044 | -0.6221 | No | ||
| 32 | SPRED2 | 510138 540195 | 15264 | -0.069 | -0.6399 | No | ||
| 33 | MATK | 380687 1410603 | 15436 | -0.083 | -0.6430 | No | ||
| 34 | MAP4K1 | 4060692 | 16525 | -0.231 | -0.6847 | Yes | ||
| 35 | BCL2 | 730132 1570736 2470138 3800044 4810037 5690068 5860504 6650164 | 16536 | -0.234 | -0.6680 | Yes | ||
| 36 | PTPN6 | 4230128 | 17006 | -0.350 | -0.6676 | Yes | ||
| 37 | GSK3B | 5360348 | 17132 | -0.395 | -0.6454 | Yes | ||
| 38 | PTEN | 3390064 | 17161 | -0.403 | -0.6173 | Yes | ||
| 39 | MAPK3 | 580161 4780035 | 17348 | -0.472 | -0.5926 | Yes | ||
| 40 | CBL | 6380068 | 17419 | -0.504 | -0.5594 | Yes | ||
| 41 | GAB1 | 2970156 | 17503 | -0.540 | -0.5242 | Yes | ||
| 42 | VAV1 | 6020487 | 17855 | -0.751 | -0.4879 | Yes | ||
| 43 | CRKL | 4050427 | 17897 | -0.783 | -0.4326 | Yes | ||
| 44 | STAT3 | 460040 3710341 | 18021 | -0.893 | -0.3736 | Yes | ||
| 45 | SOCS1 | 730139 | 18113 | -1.004 | -0.3048 | Yes | ||
| 46 | STAT1 | 6510204 6590553 | 18176 | -1.089 | -0.2281 | Yes | ||
| 47 | PDPK1 | 6650168 | 18263 | -1.250 | -0.1409 | Yes | ||
| 48 | TEC | 1400576 | 18505 | -2.176 | 0.0060 | Yes |
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